Synthesis, Characterization and In-Vitro Toxicity Assessment of Superparamagnetic Iron Oxide Nanoparticles for Biomedical Applications

On the growing clinical demands, superparamagnetic iron oxide nanoparticles (SPIONs) have a vital role due to their infinite physical and chemical properties at nanoscale. The researchers started focus more on magnetite nanoparticle applications with unique shape size in various filed such as biomedicine, food environment synthesize Fe3O4 NP. Here we synthesized SPIONs-Fe3O4 NP successfully by co-precipitation technique. prepared were characterized using suitable analytical tools for structural, morphological, elemental, optical thermogravimetric analysis. Moreover, genotoxicity hemolysis assay test has been carried out estimate toxicity of concentrations. results found that 25 μg/mL concentration shows good hemocompatibility than other was examined Allium cepa (onion root tips) chromosomal aberration. Hence, present study discusses synthesis characterization, assessing potential NPs.